Company Filing History:
Years Active: 2010-2013
Title: **Ingrid Tagen: Innovator in Viral Expression and Plasmid Technology**
Introduction
Ingrid Tagen, a distinguished inventor based in Tartu, Estonia, has made significant contributions to the fields of protein, antibody, and enzyme production through her innovative patents. With two patents to her name, Ingrid has demonstrated her expertise in viral expression systems and their applications in advancing biomedical research.
Latest Patents
One of Ingrid's notable patents focuses on "Viral expression plasmids for production of proteins, antibodies, enzymes, virus-like particles and for use in cell-based assays." This groundbreaking work reveals the potential of the Epstein-Barr virus (EBV) FR-element, which incorporates EBNA1 multimeric binding sites, to ensure stable maintenance replication of mouse polyomavirus (PyV) core origin plasmids. The findings indicate effective replication functions in the presence of BPV-1 E2 protein and PyV large T-antigen (LT).
Her second patent, titled "Vectors, cell lines and their use in obtaining extended episomal maintenance replication of hybrid plasmids and expression of gene products," further explores the role of BPV-1 E2 protein-dependent minichromosome maintenance elements. This research demonstrates that MME-dependent plasmids can maintain a low loss frequency of merely 6% per generation, allowing for prolonged stable maintenance without selection pressure. The data confirm that maintenance functions derived from various viruses can facilitate the segregation and partitioning of heterologous origins, thereby enhancing gene product expression.
Career Highlights
Ingrid has been affiliated with several prominent companies, including Kosagen Cell Factory OÜ and Icosagen Cell Factory OÜ. Her work in these organizations has been pivotal in the context of cellular and molecular biology, contributing to innovative solutions in the production of biopharmaceuticals.
Collaborations
Throughout her career, Ingrid has collaborated with notable professionals such as Toomas Silla and Jelizaveta Geimanen. These collaborations have not only enriched her research but have also fostered an exchange of ideas that contribute to advancements in the field.
Conclusion
Ingrid Tagen stands out as a valuable innovator in the realm of viral expression and plasmid technologies. Her patents reflect her commitment to advancing scientific knowledge and improving methodologies in protein and enzyme production, solidifying her impact on the biotechnology landscape. As her work continues to evolve, Ingrid remains a key figure in transforming innovative ideas into practical applications within the life sciences.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.