Iimura Shin

Title: Iimura Shin: Innovator in VLA-4 Inhibitor Compounds

Introduction

Iimura Shin is a notable inventor based in Tokyo, Japan. He has made significant contributions to the field of medicinal chemistry, particularly in the development of compounds that target specific biological pathways. His work focuses on the inhibition of VLA-4, a crucial integrin involved in various medical conditions.

Latest Patents

Iimura Shin holds a patent for VLA-4 inhibitor compounds. These compounds selectively inhibit the binding of ligands to α4β1 integrin (VLA-4) and detail methods for their preparation. The compounds are represented by a specific formula and serve as selective inhibitors of VLA-4 mediated cell adhesion. They are particularly useful in treating conditions associated with such adhesion, including inflammatory and autoimmune responses, diabetes, asthma, psoriasis, inflammatory bowel disease, transplantation rejection, and tumor metastasis.

Career Highlights

Throughout his career, Iimura Shin has worked with prominent companies in the pharmaceutical industry. Notably, he has been associated with Daiichi Pharmaceutical Co., Ltd. and Pharmacopeia Drug Discovery, Inc. His expertise in drug discovery and development has positioned him as a valuable asset in the field.

Collaborations

Iimura Shin has collaborated with esteemed colleagues, including John J Baldwin and Edward McDonald. These partnerships have contributed to the advancement of his research and the successful development of innovative therapeutic solutions.

Conclusion

Iimura Shin's work in developing VLA-4 inhibitor compounds showcases his dedication to addressing critical health issues through innovative solutions. His contributions to medicinal chemistry continue to have a lasting impact on the treatment of various medical conditions.