This inventor holds 2 USPTO granted patents. Top assignees: University System of Maryland, Other. Active years: 1997-2002.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 2,027 
1 out of 834,513 Years Active: 1997-2002
Title: Innovations by Ih-Chang Hsu
Introduction
Ih-Chang Hsu is a notable inventor based in Ellicott City, MD (US). He has made significant contributions to the field of molecular biology, particularly in the area of DNA and RNA analysis. With a total of 2 patents, his work has advanced the methods used for detecting genetic sequences.
Latest Patents
Hsu's latest patents include a method of amplifying DNA and RNA mismatch cleavage products. This innovative technique enhances the detection of probe fragment products of base pair mismatch cleavage, indicating the presence and sequence of target DNA. The method involves maintaining an assay temperature that optimizes the amplification process through recycling targets. The use of an amplifier, such as ammonium acetate or an amine derivative, plays a crucial role in releasing the target from the complex, thereby amplifying the detectable signal.
Another significant patent by Hsu is a method for identifying a nucleotide base pair at a point mutation site. This invention utilizes mismatch endonucleases and a set of labeled oligonucleotide probes to identify single base pair mismatches in nucleic acids. The formation of a detectable enzyme-nucleic acid-probe complex or labeled cleaved fragments occurs when a base pair mismatch is present, showcasing the effectiveness of this method in genetic analysis.
Career Highlights
Throughout his career, Ih-Chang Hsu has worked with various institutions, including the University System of Maryland. His expertise in molecular biology has positioned him as a valuable contributor to advancements in genetic research.
Collaborations
Hsu has collaborated with notable individuals in his field, including William E Highsmith, Jr. and James W Shih. These collaborations have further enriched his research and innovations.
Conclusion
Ih-Chang Hsu's contributions to the field of molecular biology through his patents demonstrate his commitment to advancing genetic analysis techniques. His innovative methods have the potential to significantly impact research and diagnostics in genetics.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile