The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 1997
Filed:
Jun. 06, 1995
Applicant:
Inventors:
A-Lien Lu-Chang, Columbia, MD (US);
Ih-Chang Hsu, Ellicott City, MD (US);
Assignee:
The University of Maryland at Baltimore, Baltimore, MD (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12P / ;
U.S. Cl.
CPC ...
435-6 ; 435 912 ; 935 77 ; 935 78 ;
Abstract
This invention relates to a method for identifying single base pair mismatches in nucleic acids using mismatch endonucleases and a set of labeled oligonucleotide probes which hybridize to mismatch sequences in the target nucleic acid such that a detectable enzyme-nucleic acid-probe complex forms or labeled cleaved fragments form when a base pair mismatch is present.