Culver, IN, United States of America

Igor R Likhotvorik


Average Co-Inventor Count = 1.5

ph-index = 2

Forward Citations = 53(Granted Patents)


Company Filing History:


Years Active: 2005-2008

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3 patents (USPTO):Explore Patents

Title: Igor R. Likhotvorik: Innovator in Opioid Analgesics Manufacturing

Introduction

Igor R. Likhotvorik is a notable inventor based in Culver, IN (US), recognized for his contributions to the field of pharmaceutical chemistry. With a focus on the innovative production of opioid analgesics, he holds three patents that demonstrate his significant expertise and inventiveness.

Latest Patents

Igor Likhotvorik's latest patents highlight his groundbreaking approaches to opioid synthesis.

1. The first patent involves a detailed process for the manufacture of dihydrothebaine, dihydrocodeinone enol acetate, hydrocodone, and their analogs. This innovative method utilizes a reaction between dihydrocodeine or its analogs with benzophenone in a hydrocarbon solvent, leading to the production of an enolate of the corresponding ketone, followed by the addition of the reaction mixture to an electrophilic agent for product isolation.

2. His second recent patent describes a one-pot process for preparing opioid analgesics such as hydrocodone, hydromorphone, and their analogs. This process involves reacting codeine, morphine, and their analogs with hydrogen in a solvent system containing benzophenone and a neutral solvent, supported by a metal catalyst and followed by oxidation with potassium tert-alkylate.

Career Highlights

Igor currently works at Acura Pharmaceuticals, Inc., where he applies his extensive knowledge in pharmaceutical processes to create safer and more effective pain relief options. His work has actively contributed to advancements in medication formulations and manufacturing techniques.

Collaborations

Throughout his career, Igor has collaborated with various professionals, including his coworker Joseph J. Lisowski. Together, they aim to enhance the efficacy and safety of opioid medications, reflecting a shared commitment to innovation in pharmaceutical science.

Conclusion

Igor R. Likhotvorik stands out as an inventor making significant strides in the field of opioid analgesics. With his three patents, he showcases a dedication to improving manufacturing processes and providing safer alternatives in pain management. His innovative methods are instrumental in propelling the pharmaceutical industry forward, ensuring better treatment options for patients in need.

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