Company Filing History:
Years Active: 2006-2010
Title: Iben Dalum: Pioneering Innovations in Therapeutic Vaccination
Introduction
Iben Dalum, an esteemed inventor based in Hørsholm, Denmark, has made significant contributions to the field of therapeutic vaccination. With a total of four patents to his name, his work focuses on innovative methods aimed at inducing cell-mediated immunity, particularly against weak antigens, including self-proteins. His latest patents reflect a commitment to advancing cancer immunotherapy.
Latest Patents
Dalum's most recent patent outlines a method for inducing cytotoxic T-lymphocyte (CTL) immunity against weak antigens, specifically targeting cancer-specific antigens such as PSM, Her2, or FGF8b. The innovative method requires antigen-presenting cells to showcase at least one CTL epitope of the weak antigen while simultaneously presenting at least one foreign T-helper lymphocyte epitope. This dual presentation can be achieved through traditional polypeptide vaccination or other approaches, including live attenuated and nucleic acid vaccinations. The patent also includes the creation of immunogenic analogues of these cancer-specific antigens and outlines nucleic acid molecules encoding these analogues, along with vectors and transformed cells. Furthermore, it provides a method for identifying immunogenic analogues of weak or non-immunogenic antigens, marking a significant advancement in therapeutic strategies against cancer.
Career Highlights
Iben Dalum has collaborated with notable companies, including Pharmexa A/S and Bn Immunotherapeutics, Inc. His experience in these organizations has likely fueled his innovative approach to immunotherapy, driving advancements that could benefit countless individuals affected by cancer.
Collaborations
During his professional journey, Dalum has worked alongside esteemed colleagues such as Søren Mouritsen and Lucilla Steinaa. Their collaborative efforts may have fostered a rich environment for research and development, ultimately leading to the unique innovations seen in his patent portfolio.
Conclusion
Iben Dalum's impact on the field of therapeutic vaccination underscores his position as a leading inventor dedicated to exploring new frontiers in cancer treatment. With his groundbreaking methods aimed at enhancing cell-mediated immunity, his work promises to contribute significantly to the ongoing fight against cancer, making him a prominent figure in the realm of medical innovations.