I-Ting Teng

Title: I-Ting Teng: Innovator in Tauopathy-Related Neurodegenerative Disorders

Introduction

I-Ting Teng is a notable inventor based in Gainesville, FL (US). He has made significant contributions to the field of neurodegenerative disorders, particularly through his innovative work on tau protein-binding DNA aptamers. His research focuses on developing therapeutic utilities for tauopathy-related conditions.

Latest Patents

I-Ting Teng holds a patent for "Tau protein-binding DNA aptamers with capture/detection and therapeutic utilities in tauopathy-related neurodegenerative disorders." This patent identifies DNA aptamers that bind to tau protein at its phosphorylatable sites. The disclosed DNA aptamers not only recognize tau at specific phosphorylatable sites but also demonstrate inhibitory effects on the phosphorylation and oligomer formation of tau protein. Molecular probes based on these DNA aptamers can be utilized as capture or detection agents to measure the levels of tau and phosphor-tau in cerebrospinal fluid. They can also be applied for cell-based or in vivo brain imaging in live animals or humans. Compositions comprising these DNA aptamers can be used to arrest or treat the progression of tauopathy associated with neurodegenerative disorders.

Career Highlights

Throughout his career, I-Ting Teng has worked with esteemed organizations, including the University of Florida Research Foundation and the United States Government as represented by the Department of Veterans Affairs. His work has been instrumental in advancing the understanding and treatment of tau-related diseases.

Collaborations

I-Ting Teng has collaborated with notable colleagues such as Ka W Wang and Weihong Tan. Their combined expertise has contributed to the success of his research endeavors.

Conclusion

I-Ting Teng's innovative work in the field of tauopathy-related neurodegenerative disorders highlights the importance of research in developing effective treatments. His contributions through patents and collaborations continue to pave the way for advancements in this critical area of health.