This inventor holds 1 USPTO granted patent, plus 1 CIPO patent. Top assignee: Syngenta Participations Ag. Active years: 2010.
Company Filing History:
Years Active: 2010
Title: The Innovations of Hur-Song Chang
Introduction
Hur-Song Chang is a notable inventor based in San Diego, CA. He has made significant contributions to the field of gene expression level detection. His innovative work has led to the development of a unique patent that enhances the accuracy of micro-array technology.
Latest Patents
Hur-Song Chang holds a patent titled "Probe correction for gene expression level detection." This patent involves a method where individual probes on micro-arrays are re-scaled and corrected using a set of probe-dependent coefficients derived from genomic-DNA hybridization signals. The process determines a dynamic range for gDNA binding by measuring a concentration signal curve. Signals for each probe are measured during multiple hybridizations within a linear range. Concentration insensitive probes are identified for two sets of experiments, and probes are discarded based on a threshold compared to their standard deviation divided by their average in each set. The correction coefficients are then utilized to calculate a corrected intensity for each probe. Probes with high uncertainty are discarded, and a weighting factor along with an uncertainty factor is determined for each probe. Ultimately, a call for each gene is made, categorizing it as absent, marginal, or present.
Career Highlights
Hur-Song Chang is currently associated with Syngenta Participations AG, where he continues to apply his expertise in the field of biotechnology. His work has been instrumental in advancing the understanding of gene expression and its implications in various biological processes.
Collaborations
He has collaborated with notable colleagues such as Yiping Fan and Xun Wang, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Hur-Song Chang's contributions to gene expression level detection through his innovative patent exemplify the impact of dedicated research in biotechnology. His work continues to influence the field and pave the way for future advancements.