Hugh D Burns

Title: Hugh D Burns: Innovator in Radiolabeled Compounds

Introduction

Hugh D Burns is a notable inventor based in Harleysville, PA (US). He has made significant contributions to the field of radiolabeled compounds, holding a total of 4 patents. His work has implications in both diagnostic and therapeutic applications.

Latest Patents

One of his latest patents is focused on radiolabeled farnesyl-protein transferase inhibitors. This invention is directed toward compounds that are useful for labeling FPTase in various assays, including cell-based, tissue-based, or whole animal studies. The tracers developed can also be utilized in competitive binding assays to gather information on the interaction of unlabeled FTIs with FPTase. Another significant patent involves thiolactone bifunctional chelating agents for diagnostic and therapeutic purposes. This bifunctional ligand is designed for use in compositions produced by reacting the ligand with compounds containing amino, thiolate, or alcholate groups, particularly proteins. The resulting chelates are complexed with metals such as technetium and rhenium, leading to various diagnostic and therapeutic applications.

Career Highlights

Hugh D Burns has worked with prestigious organizations, including The Johns Hopkins University and Merck & Company, Inc. His experience in these institutions has allowed him to advance his research and contribute to the scientific community.

Collaborations

Some of his notable coworkers include Alfred V Kramer and Susan Z Lever. Their collaborative efforts have likely enhanced the quality and impact of his inventions.

Conclusion

Hugh D Burns is a distinguished inventor whose work in radiolabeled compounds has paved the way for advancements in diagnostic and therapeutic applications. His contributions continue to influence the field and inspire future innovations.