Company Filing History:
Years Active: 1994-2002
Title: Hsin Tsai: Innovator in Biotechnology
Introduction
Hsin Tsai is a prominent inventor based in Taipei, Taiwan. He has made significant contributions to the field of biotechnology, particularly in the development of enzymes for pharmaceutical applications. With a total of six patents to his name, Tsai's work has the potential to impact various aspects of drug development and production.
Latest Patents
One of Hsin Tsai's latest patents is focused on a mutant D-amino acid aminotransferase. This invention relates to the simultaneous production of glutaryl-7-aminocephalosporanic acid and D-amino acid. The patent describes a mutant D-amino acid aminotransferase that is obtained by substituting the glutamate residue at position 13 of the wild-type enzyme with hydrophobic amino acids. This mutant enzyme can be utilized in the production of D-amino acid and the conversion of glutaryl-7-aminocephalosporanic acid from cephalosporin C. Additionally, the patent includes a replica-paper staining method for screening cells that express high DAT activity.
Another notable patent by Tsai is for a mutant aspartase. This invention comprises a mutant aspartase that includes the amino acid sequence of a wild-type E. coli aspartase, with a substitution at one of the positions 25, 123, 421, or 463. The patent also outlines a process for preparing this mutant aspartase, which could have various applications in biotechnology.
Career Highlights
Hsin Tsai is affiliated with the Development Center for Biotechnology, where he continues to innovate and contribute to the field. His work has garnered attention for its potential applications in the pharmaceutical industry, particularly in the development of new drugs and therapies.
Collaborations
Tsai has collaborated with notable colleagues, including Chein-Shyong Su and Wuen-Hsian Huang. These partnerships have likely enhanced the scope and impact of his research, leading to advancements in biotechnology.
Conclusion
Hsin Tsai is a distinguished inventor whose work in biotechnology has led to several important patents. His innovations in enzyme development are paving the way for advancements in drug production and pharmaceutical applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.