Howard Y Chang

Title: Howard Y Chang: Pioneer in Circular RNA Innovations

Introduction: Howard Y Chang, an esteemed inventor based in Stanford, CA, has made significant contributions to the field of molecular biology and immunology through his innovative research. With a noteworthy portfolio of 14 patents, Chang has been instrumental in advancing our understanding of circular RNAs and their applications.

Latest Patents: Among his most recent patents, Chang focuses on the potential of circular RNAs in modulating immune responses. One notable patent discusses compositions and methods for modifying RNA through circularization, particularly emphasizing the generation of circular RNAs with exogenous introns to stimulate innate immune responses or with endogenous introns to prevent immune recognition of foreign RNA. Another key patent outlines recombinant circular RNA molecules that include an internal ribosome entry site (IRES) linked to protein-coding sequences, enabling novel methods for protein production in cells.

Career Highlights: Howard Y Chang has had a remarkable academic career with affiliations to prestigious institutions such as Leland Stanford Junior University and Emory University. His dedication and innovative approach have earned him recognition in the scientific community, particularly for his research on circular RNA and its inherent capabilities.

Collaborations: Throughout his career, Chang has collaborated with fellow researchers like Jason D Buenrostro and William J Greenleaf. These partnerships have facilitated a productive exchange of ideas and significant advancements in the understanding of RNA biology.

Conclusion: Howard Y Chang stands out as a prominent inventor and researcher whose work with circular RNAs is paving the way for new therapeutic approaches in immunology. With a growing list of patents and a commitment to innovation, Chang's contributions continue to influence the field and inspire future research.