Howard Sard

Title: Howard Sard: Inventor in Pharmaceutical Chemistry

Introduction

Howard Sard is an inventor associated with Arlington, Massachusetts, and Medicis Pharmaceutical Corporation. His patent work concerns crystalline and liquid crystalline forms of 25-hydroxy-cholest-5-en-3-sulfate sodium, also known as 25HC3S.

Latest Patents

Sard is named on one patent, titled “Crystalline and Liquid Crystalline 25-Hydroxy-Cholest-5-En-3-Sulfate Sodium and Methods for Preparing Same.” The patent describes Forms I, II, III, V, IX, XI, and XIII of 25HC3S sodium, as well as combinations of these forms. It also covers pharmaceutical formulations and methods for preparing 25HC3S.

The disclosed methods address potential treatment or prevention of hypercholesterolemia, hypertriglyceridemia, and conditions associated with fat accumulation and inflammation. Examples include non-alcoholic fatty liver disease, non-alcoholic steatohepatitis, alcoholic hepatitis, acute kidney injury, psoriasis, and atherosclerosis. Sard’s listed patent portfolio comprises 1 patent.

Career Highlights

Sard’s documented patent contribution focuses on pharmaceutical compounds, their crystalline forms, and preparation methods. The patent also describes possible pharmaceutical applications of those forms.

Collaborations

The patent lists Andrew R. Miksztal and Shawn Johnstone among Sard’s coworkers. Their shared work is associated with the disclosed 25HC3S sodium forms, formulations, and preparation methods.

Conclusion

Howard Sard’s patent record highlights work in pharmaceutical chemistry, particularly the forms and potential applications of 25HC3S sodium.