Howard Sands

Title: The Innovations of Howard Sands

Introduction

Howard Sands is a notable inventor based in Wilmington, DE (US), recognized for his contributions to the field of biotechnology. With a total of 5 patents, Sands has made significant advancements in the development of antibodies and methods for treating diseases associated with abnormal cell proliferation.

Latest Patents

Sands' latest patents include groundbreaking work on antibodies and methods for generating genetically altered antibodies with enhanced effector function. His research focuses on using dominant negative alleles of human mismatch repair genes to create hypermutable cells and organisms. This innovative approach allows for the efficient preparation of new cell lines and animal varieties with novel properties, enhancing genetic diversity within immunoglobulin genes. Additionally, Sands has developed methods for increasing the effector function of monoclonal antibodies, which are crucial for improving therapeutic outcomes. Another significant patent involves methods for administering paclitaxel, a drug used to treat cancer. By formulating paclitaxel with vitamin E derivatives, Sands has found ways to avoid acute hypersensitivity reactions and potentially increase the drug's therapeutic index.

Career Highlights

Throughout his career, Sands has worked with various companies, including Supergen, Inc. His work has been instrumental in advancing the field of biotechnology, particularly in the development of therapeutic methods and antibody production.

Collaborations

Sands has collaborated with notable colleagues such as Awadhesh K Mishra and Rajashree Joshi-Hangal, contributing to the success of his innovative projects.

Conclusion

Howard Sands is a distinguished inventor whose work in biotechnology has led to significant advancements in antibody development and cancer treatment methods. His contributions continue to impact the field positively, showcasing the importance of innovation in healthcare.