Hisami Yamaguchi

Title: **Innovative Contributions of Hisami Yamaguchi in Pharmaceutical Development**

Introduction

Hisami Yamaguchi, a talented inventor based in Nishinomiya, Japan, has made significant strides in the field of pharmaceuticals. With a total of three patents to her name, Yamaguchi has demonstrated a profound commitment to enhancing drug delivery systems, especially in terms of usability and effectiveness.

Latest Patents

Yamaguchi's latest patents highlight her innovative approach to pharmaceutical formulations. One of her notable inventions is the development of a &bgr;-lactam antibiotic-containing tablet that is designed to be easily swallowable, particularly for the elderly who may struggle with traditional tablet forms. These tablets contain 60-85% by weight of a &bgr;-lactam antibiotic, a disintegrator composed of low-substituted hydroxypropylcellulose and/or crosslinked polyvinylpyrrolidone, and a binder ranging from 0.5-2% by weight. The invention simplifies the process of drug administration, allowing for dispersions that self-disintegrate upon contact with water.

Another remarkable creation by Yamaguchi is the Time-Controlled Explosion System. This innovative system allows for drug release through an explosion mechanism after a predetermined time, utilizing preparations in the form of beads or granules. The preparations consist of a core, a drug, a swelling agent, and an outer membrane made of a water-insoluble coating material.

Career Highlights

Hisami Yamaguchi works with Fujisawa Pharmaceutical Company, Ltd., where she collaborates with coworkers, including Yoshio Ueda and Takehisa Hata. Her contributions not only enhance the company's product offerings but also improve patient care through more effective medication delivery systems.

Collaborations

Collaboration plays a crucial role in Yamaguchi's inventive processes. Working alongside experienced professionals like Yoshio Ueda and Takehisa Hata, she has been able to leverage diverse expertise, leading to successful advancements in pharmaceutical technology. These collaborations enhance her ability to innovate, ultimately benefiting the broader field of medicine.

Conclusion

Hisami Yamaguchi exemplifies the spirit of innovation within the pharmaceutical industry, driven by a desire to improve patient experiences and outcomes. Her patented inventions reflect her dedication to creating practical solutions for medication administration. As she continues her work at Fujisawa Pharmaceutical Company, Ltd., Yamaguchi’s contributions will undoubtedly continue to influence the landscape of pharmaceutical development in the years to come.