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For the Inventor, By the Inventor

Yokohama, Japan

Hiroshi Tone

USPTO Granted Patents = 13

Average Co-Inventor Count = 6.9

ph-index = 5

Forward Citations = 88(Granted Patents)


Location History:

  • Fujisawa, JA (1976 - 1978)
  • Yokohama, JP (1990 - 2000)

Company Filing History:

goldMedal5 out of 40 
 
Mercian Corporation
 patents
silverMedal5 out of 21 
 
Sanraku Incorporated
 patents
bronzeMedal2 out of 37 
 
Sanraku-ocean Co., Ltd.
 patents
4. 2 out of 212 
 
Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
 patents
where one patent can have more than one assignee

Years Active: 1976-2000

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13 patents (USPTO):
1. 6020363 - Isocoumarin derivatives and use thereof in drugs (2000-02-01),
2. 5322937 - Genes encoding a 3-acylation enzyme for macrolide antibiotics (1994-06-21),
3. 5240849 - DNA coding for enzyme capable of acylating the 4'-position of macrolide (1993-08-31),
4. 5223519 - 4-hydroxypyridine derivatives, useful for treating circulatory diseases (1993-06-29),
5. 5183883 - Conjugate of adriamycin and cyclodextrin (1993-02-02),
6. 5149802 - Process for producing azetidinone derivatives (1992-09-22),
7. 5091370 - Angolamycin derivatives (1992-02-25),
8. 5055259 - Bloodless blood typing training kit (1991-10-08),
9. 4997922 - Anthracycline derivatives (1991-03-05),
10. 4933439 - Tylosin derivatives and processes for producing the same (1990-06-12),
11. 4070458 - Novel physiologically active peptide and its n-acyl derivatives and (1978-01-24),
12. 4055468 - Processes for producing physiologically active peptide and its N-acyl (1977-10-25),
13. 3992524 - Antitumor antibiotic macracidmycin (1976-11-16),

Title: The Innovative Contributions of Hiroshi Tone

Introduction: Hiroshi Tone, an accomplished inventor based in Yokohama, Japan, has made significant strides in the field of pharmaceuticals and biotechnology. With a total of 13 patents to his name, Tone's work focuses on the development of novel compounds and methodologies that advance medical science.

Latest Patents: Among his latest innovations, Tone has patented isocoumarin derivatives and their applications in drug development. Additionally, he has contributed to the field with a patent concerning genes encoding a 3-acylation enzyme for macrolide antibiotics. This invention includes a DNA fragment derived from a strain within the genus Streptomyces, which has critical applications in producing 3-acylated macrolide antibiotics. The specific DNA fragments are characterized by their lengths of approximately 1.8 kb and 3.2 kb, as detailed in the accompanying restriction enzyme maps.

Career Highlights: Hiroshi Tone has had a notable career, contributing his expertise in various reputable organizations. He has worked with Mercian Corporation and Sanraku Incorporated, where he utilized his scientific knowledge to drive innovation in pharmaceutical research and development.

Collaborations: Throughout his career, Tone has collaborated with several esteemed colleagues, including Rokuro Okamoto and Takeo Yoshioka. These partnerships have fostered a rich environment for innovation and have resulted in valuable advancements in their respective fields.

Conclusion: Hiroshi Tone's commitment to innovation in pharmaceuticals is evidenced by his impressive portfolio of patents and collaborations. As he continues to develop groundbreaking solutions in drug development, his contributions are likely to have a lasting impact on the biotechnology and pharmaceutical industries.

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