This inventor holds 1 USPTO granted patent. Top assignees: Teijin Limited, The Chemo-Sero-Therapeutic Res. Inst.. Active years: 1987.
Company Filing History:
1 out of 1,605 
1 out of 1 Years Active: 1987
Title: Hiroshi Koba: Innovator in Pertussis Vaccine Production
Introduction
Hiroshi Koba is a notable inventor based in Kumamoto, Japan. He has made significant contributions to the field of vaccine production, particularly in developing methods for producing protective antigens.
Latest Patents
Hiroshi Koba holds a patent for a method for the production of HA fraction containing protective antigens. This method involves producing a HA fraction from Bordetella pertussis on an industrial scale. The process includes inoculating a strain of B. pertussis in a liquid culture with cyclodextrin or its derivatives, culturing it under controlled conditions, and harvesting the HA fraction at specific growth phases. Additionally, the patent outlines a method for creating a pertussis vaccine from the HA fraction by formalinizing it in the presence of an amino acid. He has 1 patent to his name.
Career Highlights
Throughout his career, Hiroshi Koba has worked with prominent organizations such as the Chemo-Sero-Therapeutic Research Institute and Teijin Limited. His work has focused on advancing vaccine technology and improving public health outcomes.
Collaborations
Hiroshi Koba has collaborated with notable colleagues, including Akihiro Ginnaga and Shin Sakuma. These partnerships have contributed to the development of innovative solutions in the field of vaccine production.
Conclusion
Hiroshi Koba's contributions to vaccine production and his innovative methods for creating protective antigens have made a significant impact in the field. His work continues to influence advancements in public health and vaccine technology.