Company Filing History:
2 out of 55 
2 out of 950 
2 out of 7 
Years Active: 2018-2021
Title: Hiroki Oshita: Innovator in Transgenic Mouse Technology
Introduction
Hiroki Oshita is an accomplished inventor based in Higashihiroshima, Japan. With a focus on advancements in medical research, he holds two patents that contribute significantly to the field of biotechnology. His innovative approaches have the potential to impact therapeutic strategies related to liver diseases.
Latest Patents
Oshita's latest inventions include a Urokinase-type plasminogen activator transgenic mouse. This invention presents a mouse model that exhibits liver damage, characterized by a high degree of harm to the original hepatocytes while possessing a uPA gene in a heterozygous form. The innovative method entails transforming mouse embryonic stem (ES) cells with a specific DNA fragment that includes liver-specific promoters/enhancers and the coding sequence for urokinase-type plasminogen activator. The steps for developing this transgenic mouse include injecting transformed ES cells into a host embryo, transplanting the embryo into a surrogate mother mouse, and breeding resulting chimeric mice to achieve the desired genetic configuration.
Career Highlights
Throughout his career, Hiroki Oshita has made significant contributions to medical science through collaboration with distinguished organizations. He has worked at the Tokyo Metropolitan Institute of Medical Science and Chugai Pharmaceutical Co., Ltd., where he has harnessed his expertise in genetics and biotechnology to drive innovation in research.
Collaborations
Oshita has had the opportunity to collaborate with esteemed colleagues such as Michinori Kohara and Koichi Jishage, who have contributed to the advancement of research and development in their respective fields. These collaborative efforts have not only enhanced his work but also fostered an environment of shared knowledge and innovation.
Conclusion
Hiroki Oshita stands out as a prominent inventor in the realm of biotechnology, particularly in the development of transgenic animal models that can facilitate research into liver diseases. His dedication to innovation and collaboration underscores his commitment to advancing scientific understanding and improving therapeutic options. As the field of medical research continues to evolve, innovators like Oshita play a critical role in shaping the future of healthcare.