Company Filing History:
Years Active: 2008-2024
Title: Hiroaki Matsunami: Innovator in Synthetic Odorant Receptors
Introduction
Hiroaki Matsunami is a prominent inventor based in Durham, NC (US), known for his significant contributions to the field of synthetic odorant receptors. With a total of 13 patents to his name, Matsunami has made remarkable advancements in understanding and enhancing odorant receptor activity.
Latest Patents
Matsunami's latest patents include groundbreaking work on synthetic odorant receptors. This invention relates to novel synthetic odorant receptors capable of cell surface localization upon cellular expression. Specifically, it provides synthetic odorant receptors with a consensus amino acid sequence derived from various odorant receptors within an odorant receptor family. This consensus sequence represents the most frequently present amino acid residues for each position, enhancing the understanding of odorant receptor functionality.
Another notable patent focuses on compositions and methods for enhancing odorant receptor activity. This invention involves polypeptides that modulate odorant receptor activation, particularly type 3 muscarinic acetylcholine receptor M3, which enhances receptor activation. The patent also outlines assays for detecting ligands specific to various odorant receptors and methods for screening polypeptide polymorphisms and mutations associated with receptor activation.
Career Highlights
Matsunami has had a distinguished career, working at esteemed institutions such as Duke University and The Rockefeller University. His research has significantly impacted the field of olfactory science, leading to a deeper understanding of how odorant receptors function and interact with various ligands.
Collaborations
Throughout his career, Matsunami has collaborated with notable colleagues, including Momoka Matsunami and Hanyi Zhuang. These collaborations have further enriched his research and contributed to the advancements in the field of synthetic odorant receptors.
Conclusion
Hiroaki Matsunami's innovative work in synthetic odorant receptors has paved the way for new discoveries in olfactory science. His contributions continue to influence research and applications in this vital area of study.
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