The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 23, 2011

Filed:

Dec. 07, 2009
Applicants:

Hiroaki Matsunami, Durham, NC (US);

Momoka Matsunami, Durham, NC (US);

Yoshiro Ishimaru, Tokyo, JP;

Inventors:

Hiroaki Matsunami, Durham, NC (US);

Momoka Matsunami, Durham, NC (US);

Yoshiro Ishimaru, Tokyo, JP;

Assignee:

Duke University, Durham, NC (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/02 (2006.01); C12N 1/20 (2006.01); C12N 15/74 (2006.01); C12P 21/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to sour taste receptors and compositions and methods thereof. In particular, the present invention provides assays and methods of screening for ligands specific for sour taste receptors. Additionally, the present invention provides methods for screening for accessory proteins and mutations, polymorphisms and other potential sour taste receptor protein mutations that are associated with disease states, and therapeutic agents, ligands, and modulators of such proteins. The present invention also provides compositions and methods for modulating sour taste receptors in vitro and in vivo.


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