Location History:
- Nagoya, JP (1996 - 2014)
- Tokyo, JP (1998 - 2018)
Company Filing History:
3 out of 191 
2 out of 27 
1 out of 1 
Years Active: 1996-2018
Title: Innovator Hideo Mochizuki: Advancements in Polysaccharide Production
Introduction
Hideo Mochizuki, an influential inventor based in Nagoya, Japan, has made significant contributions to the field of glycosaminoglycan research. With an impressive portfolio of 8 patents, his innovations primarily focus on methods for producing polysaccharides, enhancing biochemical processes crucial for various applications.
Latest Patents
Among his latest innovations are the patents for "Heparosan-glucuronic acid-5-epimerase," and the subsequent method for producing polysaccharide using this enzyme. This invention provides a powerful polypeptide that exhibits heparosan-glucuronate 5-epimerase activity. The method enables the production of polysaccharides wherein hexuronic acid residues are epimerized. Through meticulous screening of cDNA libraries, Mochizuki has successfully isolated a DNA sequence that encodes for this polypeptide. The epimerase effectively modifies glucuronic acid residues found in N-acetyl heparosan and iduronic acid residues of completely desulfated N-acetylated heparin. By expressing this polypeptide in insect cells, he facilitates the generation of active enzymes that yield epimerized polysaccharides, pushing the boundaries of glycosaminoglycan synthesis.
Career Highlights
Throughout his career, Hideo Mochizuki has worked with renowned organizations, notably Seikagaku Corporation and Seikagaku Kogyo Kabushiki Kaisha. His tenure at these companies has allowed him to focus on groundbreaking research, driving innovation in glycosaminoglycan production and utilization.
Collaborations
Mochizuki collaborated with prominent colleagues such as Nobukazu Hashimoto and Akio Hamai, together enhancing the depth of research and development within their projects. Their collective expertise has likely played a pivotal role in advancing their shared innovations.
Conclusion
Hideo Mochizuki stands out as a leading inventor in the realm of polysaccharide research, with his advancements promising exciting possibilities for future applications. His dedication to innovation and collaboration with fellow researchers continues to inspire developments in the field, setting the stage for further groundbreaking discoveries.