Hidemi Toyoda

Title: The Innovative Contributions of Hidemi Toyoda

Introduction

Hidemi Toyoda is a prominent inventor based in E. Setauket, NY (US). He has made significant contributions to the field of virology, particularly in the development of novel poliovirus treatments. With a total of 2 patents, his work is paving the way for advancements in oncolytic therapies.

Latest Patents

Toyoda's latest patents focus on an attenuated poliovirus that is engineered to replicate in neuroblastoma cells. This innovative approach involves the incorporation of an indigenous replication element (cre) into the 5' non-translated genomic region while inactivating the native cre element located in the coding region of 2C (mono-crePV). The stably attenuated poliovirus has shown effectiveness in a neuroblastoma model (Neuro-2a tumors) that expresses CD155, the poliovirus receptor. This development holds promise for oncolytic treatment and potential cures for solid tumors, such as neuroblastoma.

Career Highlights

Hidemi Toyoda is affiliated with the State University of New York, where he continues to conduct research and develop innovative solutions in the field of virology. His work has garnered attention for its potential impact on cancer treatment and the understanding of viral mechanisms.

Collaborations

Throughout his career, Toyoda has collaborated with notable researchers, including Eckard Wimmer and Jeronimo Cello. These partnerships have contributed to the advancement of his research and the exploration of new therapeutic avenues.

Conclusion

Hidemi Toyoda's contributions to the field of virology, particularly through his innovative patents on attenuated poliovirus, highlight his role as a leading inventor in cancer treatment research. His work continues to inspire advancements in oncolytic therapies and offers hope for effective treatments for solid tumors.