Location History:
- Noda, JP (1995)
- Koshigaya, JP (1999)
Company Filing History:
2 out of 235 
1 out of 30 Years Active: 1995-1999
Title: Innovations of Inventor Hideko Otake
Introduction
Hideko Otake is a prominent inventor based in Noda, Japan. She has made significant contributions to the field of biotechnology, particularly in the development of enzymes and recombinant DNA technologies. With a total of 2 patents, her work has the potential to impact various industrial applications.
Latest Patents
Otake's latest patents include the N-acetylmannosamine dehydrogenase gene and a novel recombinant DNA derived from a microorganism belonging to the genus Flavobacterium, specifically Flavobacterium sp. No. 141-8 strain. This invention is defined by a specific restriction enzyme map and encodes a 271 amino acid sequence. The recombinant DNA allows for the production of N-acetylmannosamine dehydrogenase in a simpler manner on an industrial scale. This enzyme is particularly useful for the quantitative determination of sialic acid. Another significant patent involves a variant E1 protein gene for the pyruvate dehydrogenase complex. This variant E1 protein exhibits high activity due to the replacement of arginine at the 146-position with proline in the amino acid sequence of the wild-type E1 protein. The invention includes a gene coding for this variant E1 protein, a novel recombinant DNA comprising the variant E1 protein-encoding gene inserted in a vector DNA, and a process for producing the variant E1 protein using the recombinant DNA.
Career Highlights
Throughout her career, Hideko Otake has worked with notable organizations, including Kikkoman Corporation and the Noda Institute for Scientific Research. Her work in these institutions has allowed her to advance her research and contribute to the field of biotechnology.
Collaborations
Otake has collaborated with esteemed colleagues such as Yasuji Koyama and Eiichi Nakano. These partnerships have further enriched her research and innovations.
Conclusion
Hideko Otake's contributions to biotechnology through her patents and collaborations highlight her role as a significant inventor in her field. Her work continues to pave the way for advancements in enzyme production and recombinant DNA technologies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.