Wyncote, PA, United States of America

Henry Z Markus


Average Co-Inventor Count = 2.7

ph-index = 8

Forward Citations = 205(Granted Patents)


Location History:

  • Wincote, PA (US) (1983)
  • Wyncote, PA (US) (1979 - 2009)

Company Filing History:


Years Active: 1979-2009

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14 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Henry Z Markus

Introduction

Henry Z Markus, an accomplished inventor based in Wyncote, Pennsylvania, has made significant contributions to the field of biotechnology. With an impressive portfolio of 14 patents, he has focused on optimizing the production of the HPV31 L1 protein, which plays a crucial role in vaccine development for papillomavirus.

Latest Patents

Markus's latest patents include groundbreaking work on the "Optimized expression of HPV 31 L1 in yeast." This invention presents synthetic DNA molecules encoding the HPV31 L1 protein, specifically designed to be free from internal transcription termination signals recognized by yeast. Moreover, the polynucleotides have been codon-optimized for high-level expression in a yeast cell. These synthetic molecules are instrumental in producing HPV31 virus-like particles (VLPs) and developing effective vaccines and pharmaceutical compositions that offer immunoprophylaxis against papillomavirus infection through neutralizing antibody and cell-mediated immunity.

Career Highlights

Throughout his career, Henry Z Markus has worked with prominent companies, including Merck & Company, Inc. His innovative research and development efforts have positioned him as a significant figure in the biotech industry, contributing to the advancement of vaccine technologies.

Collaborations

In his journey, Markus has collaborated with notable professionals, including William J McAleer and Loren D Schultz. These collaborations have enriched his work, fostering an environment of shared knowledge and innovation that has led to successful patents and groundbreaking research in biotechnology.

Conclusion

Henry Z Markus's contributions to the field through his patents and collaborations with industry professionals underscore his importance as an inventor. His work in optimizing the expression of the HPV31 L1 protein represents a significant step towards effective vaccine development, showcasing his commitment to improving public health through innovation.

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