Henry M Grage, Jr

Title: Innovations by Henry M Grage, Jr.

Introduction

Henry M Grage, Jr. is a notable inventor based in Carmel, IN (US). He has made significant contributions to the field of medical diagnostics, particularly in the development of coagulation assay devices. With a total of 3 patents to his name, Grage's work has had a meaningful impact on the industry.

Latest Patents

One of his latest patents is a method and apparatus for manufacturing a coagulation assay device. This invention involves a ribbon-like flat web that has a plurality of side-by-side depressions. The web is fed through a horizontal slot with a downward-facing surface that has an aperture communicating with a reservoir of reagent-containing solution. The method ensures that the solution is fed into the upward-facing depressions while maintaining a seal. After the solution emerges from the dispensing apparatus, it is dried in hot air, followed by the spray application of a second solution, further drying, and the application of a backing to form capillary chambers. This method is particularly useful for manufacturing coagulation assays that include magnetic particles and thromboplastin.

Another significant patent by Grage is a test carrier and method for the analytical determination of components. This invention features a carrier layer with several test layers that are at least partly in fluid contact with one another, allowing for liquid exchange. The carrier layer includes an application zone, a detection zone for producing a detectable signal, and an absorption zone with a test layer made of absorbent material. The design enables reproducible dosing of the reaction layer with a sample, enhancing the accuracy of analytical determinations.

Career Highlights

Henry M Grage, Jr. is associated with Boehringer Mannheim GmbH, where he has contributed to various innovative projects. His work has been instrumental in advancing diagnostic technologies that are crucial for medical applications.

Collaborations

Grage has collaborated with notable colleagues such as Mark T Skarstedt and Dieter Berger, further enhancing the quality and impact of his inventions.

Conclusion

Henry M Grage, Jr. is a distinguished inventor whose innovations in coagulation assay devices and analytical determination methods have significantly advanced medical diagnostics. His contributions continue to influence the field and improve healthcare outcomes.