Cranston, RI, United States of America

Henry A Santangini


Average Co-Inventor Count = 7.0

ph-index = 1

Forward Citations = 6(Granted Patents)


Company Filing History:


Years Active: 1998-2000

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2 patents (USPTO):Explore Patents

Title: Innovations by Henry A. Santangini

Introduction

Henry A. Santangini is an accomplished inventor based in Cranston, RI (US). He has made significant contributions to the field of biomedical engineering, particularly in the development of artificial liver support systems. With a total of 2 patents to his name, Santangini's work focuses on enhancing the viability and metabolic activity of cryopreserved hepatocytes.

Latest Patents

Santangini's latest patents include a method of cryopreserving hepatocytes and a system that ensures high viability and metabolic activity of these cells. The first patent describes an artificial liver support system that comprises cryopreserved hepatocytes with an initial viability of 80-99%. This innovative method involves dispensing hepatocytes into freezing containers, freezing them at temperatures ranging from minus 50 to minus 90 degrees Celsius, and storing them in liquid or vapor nitrogen. The process concludes with thawing the cryopreserved hepatocytes when needed and removing any residual cryoprotectant media. The second patent similarly outlines a system that maintains an initial viability of 80-99% and a metabolic activity of 50-80% compared to fresh hepatocytes, utilizing the same cryopreservation techniques.

Career Highlights

Henry A. Santangini is currently associated with Circe Biomedical, Inc., where he continues to innovate in the field of artificial organ support systems. His work has the potential to significantly impact patients requiring liver support, showcasing his dedication to advancing medical technology.

Collaborations

Some of Santangini's notable coworkers include Claudy Jean-Paul Mullon and Shawn P. Cain. Their collaborative efforts contribute to the ongoing research and development at Circe Biomedical, Inc.

Conclusion

Henry A. Santangini's contributions to the field of biomedical engineering through his innovative patents demonstrate his commitment to improving medical technologies. His work in cryopreservation and artificial liver support systems is paving the way for advancements in patient care.

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