The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 18, 1998
Filed:
Apr. 04, 1996
Claudy Jean-Paul Mullon, Framingham, MA (US);
Shawn Paul Cain, N. Chelmsford, MA (US);
Timothy Jon Perlman, Lexington, MA (US);
Hugo O Jauregui, Providence, RI (US);
Sharda Naik, Cranston, RI (US);
Henry A Santangini, Cranston, RI (US);
Donna M Trenkler, Greene, RI (US);
Circe Biomedical, Inc., Lexington, MA (US);
Abstract
An artificial liver support system is described herein which comprises cryopreserved hepatocytes having an initial viability of 80-99% and a metabolic activity 50-80% of fresh hepatocytes. Further disclosed are hepatocytes cryopreserved by dispensing hepatocytes into freezing containers, freezing the containers from between minus 50 to minus 90 degrees Celsius, storing the containers in liquid or vapor nitrogen, thawing the cryopreserved hepatocytes when ready for use and removing residual cryoprotectant media.