Henri M Sasmor

Title: The Innovative Contributions of Henri M. Sasmor: Revolutionizing Protein Production

Introduction: Henri M. Sasmor, an accomplished inventor based in Oceanside, CA, has made significant strides in the field of bioprocessing, contributing to four innovative patents. His work demonstrates a commitment to advancing the rapid production of protein biologics, which has important implications for various industries, including pharmaceuticals and biotechnology.

Latest Patents: Sasmor's most notable invention is a portable fluidic platform for rapid cell-free production of protein biologics. This cutting-edge technology features a bioreactor system that utilizes stable and robust cell-free translation systems. The fluidic platform integrates modular protein separation functionalities, such as size exclusion, ion exchange, and affinity chromatography systems, allowing for the purification of cell-free expressed products. This versatility enables the process-specific isolation of different proteins and their formulation. Notably, the bioreactor utilizes lysates from engineered eukaryotic (e.g., yeast) or prokaryotic (e.g., bacterial) strains, ensuring optimized protein folding and post-translational modifications. The platform's combination of purification modules on a single fluidic setup allows for flexible re-routing to meet specific target requirements. Furthermore, the system includes self-contained disposable fluidic cartridges that prevent cross-contamination, allowing for the rapid production of protein biologics—achievable within 24 hours, from DNA to purified product.

Career Highlights: Henri M. Sasmor has built a remarkable career, with pivotal roles at leading organizations such as Leidos, Inc. and Isis Pharmaceuticals, Inc. His expertise and innovative mindset have led to the creation of groundbreaking solutions that enhance productivity and flexibility in protein production methodologies.

Collaborations: Throughout his career, Sasmor has collaborated with notable professionals in the industry, including John Dresios and Richard Holmes Griffey. These partnerships have been instrumental in driving forward research and development initiatives that push the boundaries of biotechnological applications.

Conclusion: Henri M. Sasmor stands out as a prominent inventor in the field of protein biologics. His latest innovations, particularly the portable fluidic platform, represent a significant advancement in the ability to produce high-quality proteins efficiently. As Sasmor continues to innovate, his contributions will undoubtedly inspire future breakthroughs in bioprocessing and biotechnology.