Company Filing History:
5 out of 415 
1 out of 1 
1 out of 832,912 Years Active: 2011-2021
Title: Exploring the Innovations of Hema Gursahani
Introduction
Hema Gursahani, an accomplished inventor based in Foster City, California, has significantly contributed to the field of biomedical innovations, particularly in drug delivery systems. With a portfolio of seven patents, her work focuses on enhancing the efficacy and safety of drug administration, addressing critical challenges in pharmacology.
Latest Patents
Among Hema Gursahani's notable inventions are her latest patents, which include groundbreaking methods for modifying drug absorption. One of her key patents revolves around "Chemically modified small molecules - Methods of modifying the rate of systemic absorption of a drug administered to a subject by a pulmonary route." This method involves covalently conjugating a hydrophilic polymer to a drug, where the drug's half-life of elimination from the lung is significantly increased through the creation of a drug-polymer conjugate. This innovation ensures a net hydrophilic character and enhances the duration of drug action, offering tremendous implications for respiratory treatments.
Another significant patent addresses the treatment of CYP2D6 alternative metabolizers. Her invention provides methods comprising the administration of a CYP2D6 bioactive drug covalently bound to a water-soluble oligomer. This approach strategically diverts the metabolism of the drug from CYP2D6 to alternative pathways, effectively alleviating issues associated with genetic polymorphisms in the CYP2D6 gene, which can vary among populations.
Career Highlights
Hema Gursahani has worked with prominent companies in the biomedical industry, including Nektar Therapeutics. Her career is marked by a dedication to advancing drug delivery technologies and addressing the nuances involved in drug metabolism.
Collaborations
Throughout her career, Gursahani has collaborated with esteemed professionals, including Timothy A. Riley and Juergen W. Pfeiffer. These collaborations have likely enriched her innovative approaches and contributed to the successful development of her patented technologies.
Conclusion
Hema Gursahani stands out as a leading figure in pharmaceutical innovation, with her patented methods paving the way for improved therapeutic strategies. Her ongoing contributions highlight the vital intersection of science and healthcare, underscoring her commitment to enhancing patient outcomes through innovative drug delivery solutions.