The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 2021
Filed:
Jun. 09, 2009
Michael A. Eldon, Redwood City, CA (US);
C. Simone Jude-fishburn, Redwood City, CA (US);
Hema Gursahani, Foster City, CA (US);
Myong Gyong Lee, Palo Alto, CA (US);
Michael A. Eldon, Redwood City, CA (US);
C. Simone Jude-Fishburn, Redwood City, CA (US);
Hema Gursahani, Foster City, CA (US);
Myong Gyong Lee, Palo Alto, CA (US);
Nektar Therapeutics, San Francisco, CA (US);
Abstract
The invention provides various methods comprising the administration of a CYP2D6 bioactive drug covalently bound to a water-soluble oligomer. Metabolism of CYP2D6 bioactive drug conjugates is diverted from CYP2D6 to alternative pathways, and the conjugates may therefore be utilized to alleviate the problems associated with interpopulation variation resulting from the genetic polymorphism in the CYP2D6 gene.