This inventor holds 2 USPTO granted patents. Top assignee: G.d. Searle & Company. Active years: 1985-1989.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1985-1989
Title: Helmut M Sassenfeld: Innovator in Polypeptide Detection
Introduction
Helmut M Sassenfeld is a notable inventor based in Benson, GB. He has made significant contributions to the field of biochemistry, particularly in the area of polypeptide detection. With a total of 2 patents to his name, Sassenfeld's work has advanced the understanding and application of fused polypeptides.
Latest Patents
Sassenfeld's latest patents include innovative methods for detecting fused polypeptides. One patent focuses on "Fused polypeptides and methods for their detection," which discloses fused-polypeptides comprising a polypeptide product and a covalently bonded charged amino acid polymer. This method allows for the quantitation of the presence of these fused-polypeptides in both crude and purified solutions. The charged amino acid polymer is hydrolyzed using an exopeptidase, leaving the polypeptide product intact. Examples in this patent utilize polyarginine and carboxypeptidase B to produce urogastrone and gamma interferon.
Another patent, titled "Process for the preparation of polypeptides utilizing a charged amino," describes a method for producing polypeptides with the aid of a polymer of charged amino acids and an exopeptidase. In this process, a DNA sequence coding for the charged amino acid polymer is inserted adjacent to one end of the polypeptide gene. The resulting polypeptide-charged amino acid polymer fusion product is isolated, and the charged amino acid polymer is hydrolyzed to yield an active polypeptide. This patent also includes examples using polyarginine and carboxypeptidase B to produce urogastrone.
Career Highlights
Sassenfeld has worked with G.D. Searle & Company, where he has been able to apply his expertise in biochemistry and polypeptide research. His innovative approaches have contributed to advancements in the detection and preparation of polypeptides, showcasing his commitment to scientific progress.
Collaborations
One of Sassenfeld's notable collaborators is Stephen J Brewer. Their partnership has likely fostered a productive exchange of ideas and expertise in their respective fields.
Conclusion
Helmut M Sassenfeld's contributions to the field of polypeptide detection and preparation have made a significant impact on
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile