Helge Zieler

This inventor holds 21 USPTO granted patents and 11 published patent applications, plus 1 CIPO patent and 2 EPO patents, primarily in Plant Biotechnology. Top assignees: Chromatin, Inc., The University of Chicago, Firmenich Incorporated. Active years: 2007-2025.

IDiyas Innovation Intelligence. (2026). Inventor Profile: Helge Zieler. Retrieved from https://idiyas.com/inventor/helge-zieler

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

Calculating rank

USPTO Granted Patents = 21 (Patent Applications = 11)

% Patents Active = 42.9

CIPO Patents = 1 (Patent Applications = 2)

EPO Patents = 2 (Patent Applications = 11)

Average Co-Inventor Count = 3.4

ph-index = 4

Forward Citations = 56(Granted Patents)

Location History:

Chicago, IL (US) (2007 - 2008)
San Diego, CA (US) (2013)
Del Mar, CA (US) (2011 - 2021)
Encinitas, CA (US) (2013 - 2021)

Company Filing History:

The University of Chicago

patents

4 out of 24

Firmenich Incorporated

patents

4. 3 out of 3

Primordial Genetics, Inc.

patents

5. 1 out of 79

Synthetic Genomics, Inc.

patents

6. 2 out of 834,601

Other

patents

where one patent can have more than one assignee

Years Active: 2007-2025

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Areas of Expertise:

High Intensity Sweeteners

Plant Centromere Compositions

Mini-Chromosomes

Altered Cells

Improved Organisms

Centromere Sequences

Crops Revenue Generation

Compositions

Methods

Biotechnology

21 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 12428662 - Methods for making high intensity sweeteners (2025-09-30),

2. 12338476 - Methods for making high intensity sweeteners (2025-06-24),

3. 12286661 - Methods for making high intensity sweeteners (2025-04-29),

4. 11198708 - Compositions for improving cells and organisms (2021-12-14),

5. 11060124 - Methods for making high intensity sweeteners (2021-07-13),

6. 10556935 - Compositions for improving cells and organisms (2020-02-11),

7. 10093922 - Compositions and methods for creating altered and improved cells and organisms (2018-10-09),

8. 10077441 - Methods and compositions for creating altered and improved cells and organisms (2018-09-18),

9. 9758810 - Identification of centromere sequences and uses therefor (2017-09-12),

10. 9200291 - Compositions and methods for creating altered and improved cells and organisms (2015-12-01),

11. 8759086 - Methods for generating or increasing revenues from crops (2014-06-24),

12. 8729341 - Plants modified with mini-chromosomes (2014-05-20),

13. 8614089 - Centromere sequences and minichromosomes (2013-12-24),

14. 8350120 - Plants modified with mini-chromosomes (2013-01-08),

15. 8222028 - Plants modified with mini-chromosomes (2012-07-17),

Title: **Helge Zieler: A Pioneer in Sweetener Innovations**

Introduction

Helge Zieler, based in Del Mar, California, is a distinguished inventor known for his significant contributions to the field of high-intensity sweeteners. With a remarkable portfolio of 19 patents, Zieler has demonstrated a commitment to advancing food science and biotechnology.

Latest Patents

Among his latest patents are groundbreaking methods for making mogroside compounds. These innovative techniques include the development of compositions such as host cells specifically designed to produce mogroside compounds efficiently. This patent not only outlines the processes used to create these sweeteners but also details the compositions, including cell lysates and recombinant cells, that incorporate the mogroside compounds.

Additionally, Zieler has introduced compositions aimed at improving cells and organisms. This invention encompasses randomized in-frame fusion polynucleotides and methods for their introduction into host organisms. These compositions are designed to induce desirable phenotypic changes that enhance the organisms' tolerance to stress, leading to the emergence of novel characteristics.

Career Highlights

Helge Zieler has worked with renowned institutions, notably Chromatin, Inc. and the University of Chicago. His tenure at these organizations has been marked by groundbreaking research and innovative approaches to sweetener development and genetic modifications in organisms.

Collaborations

Throughout his career, Zieler has collaborated with prominent figures in the field, including Gregory Paul Copenhaver and Daphne Preuss. These partnerships have been instrumental in driving forward the research and development in sweetener technologies and genetic advancements.

Conclusion

Helge Zieler's contributions to the world of innovations in high-intensity sweeteners and biotechnology are remarkable. His extensive patent portfolio reflects his dedication to scientific exploration and innovation, paving the way for future advancements in the industry. As he continues his work, Zieler's legacy as a pioneering inventor is poised to leave a lasting impact on food science and beyond.

Profile summary based on public USPTO records.