The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 18, 2018

Filed:

Jan. 09, 2015
Applicant:

Helge Zieler, Del Mar, CA (US);

Inventor:

Helge Zieler, Del Mar, CA (US);

Assignee:

PRIMORDIAL GENETICS INC., Del Mar, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/74 (2006.01); C12P 21/04 (2006.01); C12P 21/06 (2006.01); C07H 21/04 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1079 (2013.01); C12N 15/10 (2013.01); C07H 21/04 (2013.01); C07K 2319/00 (2013.01); C12N 15/74 (2013.01);
Abstract

The present invention relates to compositions involving randomized in-frame fusion polynucleotides and their introduction into a host organism to identify desirable phenotypic changes. The present invention further relates to methods of generating these randomized in-frame fusion polynucleotides by introducing randomized in-frame fusion polynucleotides into an organism, selecting for organisms with new or altered phenotypes, re-isolating the randomized in-frame fusion polynucleotides from the selected organisms, re-assembling the constituent polynucleotides of the re-isolated randomized in-frame fusion polynucleotides into new collections of randomized in-frame fusion polynucleotides, and repeating the selection for organisms with new or altered phenotypes.


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