Company Filing History:
Years Active: 1998-2004
Title: Helene S. Smith: Innovator in Cancer Prognostics
Introduction
Helene S. Smith is a prominent inventor based in San Francisco, CA, known for her significant contributions to cancer research. With a total of three patents, her work focuses on innovative methods for predicting the progression of breast tissue to carcinoma. Her research has the potential to greatly impact cancer diagnosis and treatment.
Latest Patents
One of her latest patents is titled "Prognostic methods for prediction of progression of normal and hyperplastic mammary cells to carcinoma." This invention encompasses methods for determining the likelihood that benign hyperplastic breast tissue or normal breast tissue adjacent to carcinoma tissue will become malignant. The methods involve substantially isolating the tissue and determining loss of heterozygosity (LOH) at chromosome 3p24 in the tissue. LOH at chromosome 3p24 serves as a prognostic indicator that the tissue may become malignant.
Another significant patent is "Methods for identifying genes amplified in cancer cells." This patent discloses new methods for detecting cancer-associated genes and obtaining corresponding cDNA fragments. The methods involve supplying RNA preparations from control cells and from various cancer cells that share a duplicated or deleted gene in the same region of a chromosome. Amplified cDNA copies are displayed and selected based on differences in RNA abundance between preparations. This research has led to the identification of four novel genes associated with breast cancer, which are particularly useful in cancer diagnosis and treatment.
Career Highlights
Helene S. Smith is affiliated with the California Pacific Medical Center, where she conducts her research. Her work has been instrumental in advancing the understanding of breast cancer and its genetic underpinnings.
Collaborations
She has collaborated with notable colleagues, including Ling-Chun Chen and Guoren Deng, to further her research efforts in cancer prognostics.
Conclusion
Helene S. Smith's innovative work in cancer research exemplifies the critical role of inventors in advancing medical science. Her patents not only enhance our understanding of cancer progression but also pave the way for improved diagnostic and treatment methods.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.