The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 03, 2004
Filed:
Oct. 18, 1996
Applicant:
Inventors:
Guoren Deng, Walnut Creek, CA (US);
You Lu, San Francisco, CA (US);
Helene S. Smith, San Francisco, CA (US);
Assignee:
California Pacific Medical Center, San Francisco, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; G01N 3/358 ; G01N 3/360 ; C07H 2/100 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; G01N 3/358 ; G01N 3/360 ; C07H 2/100 ;
Abstract
The present invention encompasses methods for determining the likelihood that benign hyperplastic breast tissue or normal breast tissue adjacent to carcinoma tissue will become malignant. The methods comprise substantially isolating the tissue; and determining loss of heterozygosity (LOH) at chromosome 3p24 in the tissue. LOH at chromosome 3p24 is a prognostic indicator that the tissue may become malignant.