Hein Te Riele

Title: Hein Te Riele: Innovator in Gene Targeting Technologies

Introduction

Hein Te Riele is a prominent inventor based in Amsterdam, Netherlands. He has made significant contributions to the field of genetic engineering, particularly in the area of gene targeting in animal cells. With a total of two patents to his name, Te Riele's work has the potential to advance genetic research and therapeutic applications.

Latest Patents

Te Riele's latest patents include innovative methods for high efficiency gene targeting in mouse embryonic stem cells. The first patent outlines a process that involves constructing a DNA molecule containing desired sequence modifications, introducing this targeting DNA into the cell, and selecting cells where the modifications have been successfully integrated via homologous recombination. The second patent focuses on gene targeting in animal cells using isogenic DNA constructs, following a similar methodology to achieve precise genetic modifications.

Career Highlights

Hein Te Riele has established himself as a key figure in genetic research through his work at Genpharm International, Inc. His expertise in gene targeting has positioned him at the forefront of advancements in genetic engineering. His contributions are not only significant in academic circles but also hold promise for practical applications in medicine and biotechnology.

Collaborations

Te Riele has collaborated with notable colleagues such as Anton J Berns and Els Robanus Maandag. These partnerships have fostered a collaborative environment that enhances the research and development of innovative genetic technologies.

Conclusion

Hein Te Riele's work in gene targeting exemplifies the impact of innovative research in genetics. His patents and collaborations contribute to the ongoing evolution of genetic engineering, paving the way for future advancements in the field.