Company Filing History:
Years Active: 2006
Title: The Innovations of Harry F. Noller: A Pioneer in Ribosome Research
Introduction
Harry F. Noller is a renowned scientist based in Santa Cruz, California. He is recognized for his significant contributions to the field of molecular biology, particularly in understanding ribosomal structure and function. His groundbreaking work has led to innovations that are vital to the field of genetic research and drug discovery.
Latest Patents
Dr. Noller holds one notable patent titled "X-ray crystal structures of functional ribosome complexes containing transfer RNA and model messenger RNAs and methods of use." This patent involves detailed 5.5 Angstrom resolution X-ray crystallographic structures of 70S ribosome complexes, which include messenger RNA and transfer RNA (tRNA) along with their analogs. The advanced resolution achieved was made possible by integrating atomic resolution structures of the individual 30S and 50S ribosomal subunits with the electron density map. This enhanced structural insight highlights differences between the 70S complex and its subunits, paving the way for pharmacophore design aimed at discovering new inhibitors or activators.
Career Highlights
Throughout his career, Harry F. Noller has made substantial contributions to our understanding of ribosomes and their biological functions. His work has not only enhanced the fundamental knowledge within molecular biology but has also opened new avenues for therapeutic developments. Working at the University of California, Noller has established himself as a leader in his field, pushing the boundaries of ribosomal research.
Collaborations
Dr. Noller's research has been bolstered by collaborations with other eminent scientists in the field. Notable among his colleagues are Jamie H. D. Cate and Marat M. Yusupov, who have worked alongside him on various research projects. Together, they have contributed to significant advancements in our understanding of ribosomal structure and function.
Conclusion
In conclusion, Harry F. Noller's innovations in ribosome structure have had a profound impact on molecular biology. His contributions not only enhance our grasp of fundamental biological processes but also serve as a foundation for future medicinal breakthroughs. As his work continues to influence and inspire, Noller's legacy as a key inventor in the realm of ribosomal research is firmly established.