Harrie Vaessen

Title: Harrie Vaessen: Innovator in Pharmaceutical Manufacturing

Introduction

Harrie Vaessen is a notable inventor based in Wijnandsrade, Netherlands. He has made significant contributions to the field of pharmaceutical manufacturing, particularly in the development of triazole compounds. With a total of 2 patents to his name, Vaessen's work has implications for the production of important medications.

Latest Patents

Harrie Vaessen's latest patents focus on the process for the manufacture of isavuconazole and ravuconazole. The invention relates to a method for producing diastereomerically and enantiomerically enriched triazole compounds. This process involves a Reformatsky reaction between a ketone and a 2-halozincpropionate ester, followed by a resolution step, preferably an enzymatic resolution with an esterase enzyme. This innovative approach enhances the efficiency and effectiveness of producing these crucial pharmaceutical compounds.

Career Highlights

Vaessen is currently associated with Basilea Pharmaceutica AG, where he continues to advance his research and development efforts. His work in this company has positioned him as a key player in the pharmaceutical industry, contributing to the development of new therapeutic options.

Collaborations

Harrie Vaessen has collaborated with notable colleagues, including Ruben Van Summeren and Daniel Mink. These partnerships have fostered a collaborative environment that enhances innovation and drives progress in their field.

Conclusion

Harrie Vaessen's contributions to pharmaceutical manufacturing through his patents and collaborations highlight his role as an influential inventor. His work continues to impact the development of essential medications, showcasing the importance of innovation in healthcare.