Company Filing History:
Years Active: 2006
Introduction
Harren Jhoti is a prominent inventor based in Cambridge, GB. He has made significant contributions to the field of structural biology through his innovative work in the synthesis and screening of ligands. His expertise has led to the development of a patented method that enhances the identification of ligands, crucial for drug discovery and design.
Latest Patents
Harren holds a patent for "Synthesis and screening of ligands using X-ray crystallography". This patent discloses a method for identifying a ligand of a target macromolecule, which involves soaking crystals of the macromolecule in a solution containing a collection of compounds. The solution can be prepared in situ or separately, without the need for purification of the compounds. The identification of any compound bound to the macromolecule crystal is facilitated by analyzing the X-ray crystal diffraction pattern obtained from the soaked crystal. This method represents a significant advancement in the field, aiding researchers in their quest to find effective compounds for therapeutic targets.
Career Highlights
Harren Jhoti has established himself as an invaluable asset at Astex Therapeutics Limited, where he applies his knowledge and skills to address complex scientific challenges. His career is marked by a commitment to innovation in therapeutic development through detailed structural insights.
Collaborations
Throughout his career, Harren has had the opportunity to collaborate with talented individuals in his field. Notably, he has worked alongside Miles Stuart Congreve and Marc O'Reilly, contributing to projects that harness their collective expertise to propel drug discovery initiatives forward.
Conclusion
Harren Jhoti’s innovative work in ligand synthesis and screening through X-ray crystallography marks him as an influential figure in the realm of biomedical research. His patent reflects a forward-thinking approach that could lead to new breakthroughs in drug design and therapeutics, showcasing the vital role inventors play in scientific advancement.