Harpal S Mangat

Title: Harpal S Mangat: Innovator in Neuroprotection

Introduction

Harpal S Mangat is a notable inventor based in Potomac, MD (US), recognized for his contributions to the field of neuroprotection. With a total of 6 patents, he has made significant strides in developing methods and compositions aimed at treating ischemic neuronal reperfusion injury.

Latest Patents

Mangat's latest patents include innovative compositions and methods for the treatment of ischemic neuronal reperfusion injury. One of his notable inventions involves a composition that may include at least a benzodiazepine class material. This composition can also incorporate components such as an antagonist of the type 3 ryanodine receptor and an NMDA blocker, which can be administered to address ischemic neuronal reperfusion injury. Another significant patent features a composition that combines dantrolene with a residue of FMOC-valine, providing faster and higher CNS penetration than previously experienced with dantrolene. This formulation may also be developed as a pro-drug or pro-pro-drug.

Career Highlights

Mangat has had a distinguished career, contributing to research and development in various esteemed institutions. He has worked at Howard University and the University of South Florida, where he has been involved in groundbreaking research.

Collaborations

Throughout his career, Mangat has collaborated with notable colleagues, including Pradeep K Karla and Gerry Ballough. These collaborations have further enriched his research and innovations in the field.

Conclusion

Harpal S Mangat's work in neuroprotection and his innovative patents highlight his significant contributions to medical science. His dedication to developing effective treatments for ischemic neuronal reperfusion injury showcases the impact of his research on improving patient outcomes.