Harold Edgar Van Wart

Title: Harold Edgar Van Wart: Innovator in Aggrecanase Research

Introduction

Harold Edgar Van Wart is a notable inventor based in Los Altos, CA (US). He has made significant contributions to the field of biochemistry, particularly in the area of aggrecanase research. With a total of 3 patents to his name, Van Wart's work has implications for various therapeutic applications.

Latest Patents

One of his latest patents is focused on human aggrecanase and nucleic acid compositions encoding the same. This invention provides polypeptides and nucleic acid compositions that are useful in research, diagnostics, and therapeutic agent screening applications. Additionally, it includes methods for inhibiting aggrecanase activity in hosts and treating disease conditions associated with aggrecanase activity, such as rheumatoid arthritis, osteoarthritis, and other joint-related diseases. Another significant patent involves peptidic procollagen C-proteinase inhibitors, which are compounds that inhibit procollagen C-proteinase and have potential pharmaceutical applications.

Career Highlights

Harold Edgar Van Wart has worked with Syntex (U.S.A.) Inc., where he has been able to apply his expertise in biochemistry to develop innovative solutions. His work has been instrumental in advancing the understanding of aggrecanase and its role in various diseases.

Collaborations

Throughout his career, Van Wart has collaborated with notable colleagues, including Sharon Marie Dankwardt and Keith Adrian Murray Walker. These collaborations have contributed to the advancement of research in their respective fields.

Conclusion

Harold Edgar Van Wart's contributions to the field of biochemistry, particularly in aggrecanase research, have paved the way for new therapeutic approaches to treat various diseases. His innovative patents and collaborations highlight his significant impact on the scientific community.