The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 22, 2006
Filed:
Sep. 17, 2003
John David Allard, Cupertino, CA (US);
Renu Anand Heller, Stanford, CA (US);
Paul Klonowski, Cambridge, MA (US);
Harold Edgar Van Wart, Los Altos, CA (US);
John David Allard, Cupertino, CA (US);
Renu Anand Heller, Stanford, CA (US);
Paul Klonowski, Cambridge, MA (US);
Harold Edgar Van Wart, Los Altos, CA (US);
Syntex (U.S.A.) LLC, Palo Alto, CA (US);
Abstract
Human aggrecanase and polypeptides related thereto, as well as nucleic acid compositions encoding the same, are provided. The subject polypeptides and nucleic acid compositions find use in a variety of applications, including research, diagnostic, and therapeutic agent screening applications. Also provided are methods of inhibiting aggrecanase activity in a host and methods of treating disease conditions associated with aggrecanase activity, e.g. rheumatoid arthritis, osteo-arthritis, infectious arthritis, gouty arthritis, psoriatic arthritis, spondolysis, sports injury, joint trauma, pulmonary disease, fibrosis, and the like.