Company Filing History:
Years Active: 2012-2013
Title: Harmen J Bussemaker: Innovator in Genetic Research
Introduction
Harmen J Bussemaker is a prominent inventor based in New York, NY (US). He has made significant contributions to the field of genetic research, holding 2 patents that focus on the intricate mechanisms of transcription factor activity and nucleotide binding factors.
Latest Patents
His latest patents include a method for identifying aQTL regions whose genotype modulates transcription factor activity. This innovative approach utilizes genetic linkage methods to uncover genetic determinants that influence transcription factor activity. The process involves generating an inferred transcription factor activity profile based on a mathematical model of gene expression regulation. Additionally, he has developed a system and method for quantifying the sequence specificity of nucleotide binding factors. This patent provides systems and methods for determining free energy parameters that predict binding affinities of nucleotide sequences, linking phenotypic measurements to nucleotide sequences to estimate relationships and obtain sequence-specific affinity parameters.
Career Highlights
Harmen J Bussemaker is affiliated with Columbia University, where he continues to advance research in genetics and molecular biology. His work has garnered attention for its potential applications in understanding gene regulation and its implications in various biological processes.
Collaborations
He has collaborated with notable colleagues, including Barrett C Foat and Ronald G Tepper, contributing to a dynamic research environment that fosters innovation and discovery.
Conclusion
Harmen J Bussemaker's contributions to genetic research through his patents and collaborations highlight his role as a key innovator in the field. His work continues to influence the understanding of genetic mechanisms and their applications in science.