Hari Subramanian

Title: Innovations by Hari Subramanian

Introduction

Hari Subramanian is an accomplished inventor based in Oakland, CA. He has made significant contributions to the field of biotechnology, particularly in the regulation of proteins and nucleic acids. With a total of 2 patents, his work has the potential to impact various applications in genetic engineering and molecular biology.

Latest Patents

Subramanian's latest patents include "Compositions and methods for regulating proteins and nucleic acids activities" and "CRISPR protein inhibitors." The first patent focuses on methods for conditionally regulating the activities of CRISPR-Cas systems. This involves providing an inactive guide RNA with a regulatory domain that can be activated by a trigger nucleic acid. The second patent utilizes fluorescence polarization to identify potential Cas inhibitors, followed by secondary screening assays to validate these inhibitors. These innovations are crucial for advancing the capabilities of RNA-guided endonucleases.

Career Highlights

Throughout his career, Subramanian has worked with prestigious organizations such as the Broad Institute, Inc. and Brigham and Women's Hospital, Inc. His experience in these institutions has allowed him to collaborate with leading experts in the field and contribute to groundbreaking research.

Collaborations

Some of his notable coworkers include Amit Choudhary and Kurt Cox. Their collaborative efforts have further enhanced the impact of Subramanian's inventions.

Conclusion

Hari Subramanian's innovative work in biotechnology, particularly in the realm of CRISPR technology, showcases his expertise and dedication to advancing scientific knowledge. His patents reflect a commitment to developing methods that can significantly influence genetic research and applications.