Company Filing History:
Years Active: 1999-2000
Title: Haolin Ni: Innovator in Viral Vaccine Development
Introduction
Haolin Ni is a prominent inventor based in Galveston, TX (US). She has made significant contributions to the field of virology and vaccine development. With a total of 2 patents, her work focuses on innovative methods for screening and selecting virus vaccine candidates.
Latest Patents
One of her latest patents is titled "Method of screening for attenuating viruses." This invention provides a method for selecting virus vaccine candidates by identifying virus variants that do not bind to brain membrane receptor preparations. The process involves several steps, including preparing a brain membrane receptor preparation, mixing it with a virus of interest, centrifuging the suspension, determining residual virus infectivity, and isolating individual membrane receptor preparation binding-resistant virus variants. These variants are useful as potential vaccine candidates.
Another notable patent is the "Non-antibiotic system for selection of recombinant mycobacteria." This invention includes a Mycobacterium-E. coli shuttle vector that contains sequences coding for a tribrid fusion. This fusion includes the M. leprae 18kDa antigen sequence, a phoA protein antigen sequence, and a non-mycobacterial, non-E. coli heterologous protein antigen sequence. The method aims to produce protective immunity in an animal or human host by administering an effective dose of recombinant mycobacteria carrying the vector.
Career Highlights
Haolin Ni has worked with esteemed organizations such as the University of Texas System and the Research Development Foundation. Her experience in these institutions has allowed her to advance her research and contribute to significant innovations in her field.
Collaborations
Throughout her career, Haolin has collaborated with notable individuals, including Alan D Barrett and David W Niesel. These collaborations have further enriched her research and development efforts.
Conclusion
Haolin Ni is a dedicated inventor whose work in viral vaccine development has the potential to make a significant impact on public health. Her innovative patents reflect her commitment to advancing scientific knowledge and improving vaccine efficacy.