The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 20, 1999

Filed:

Apr. 11, 1997
Applicant:
Inventors:

Alan D Barrett, Galveston, TX (US);

David Niesel, League City, TX (US);

Christopher Robb, Galveston, TX (US);

Haolin Ni, Galveston, TX (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12P / ; A61K / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435 697 ; 4241841 ; 4241991 ; 4242041 ; 4351723 ; 4352531 ; 935 14 ; 935 29 ; 935 41 ; 935 45 ;
Abstract

The present invention provides a Mycobacterium-E. coli shuttle vector containing sequences coding for a tribrid fusion containing the M. leprae 18kDa antigen sequence, a phoA protein antigen sequence and a non-mycobacterial, non-E.coli heterologous protein antigen sequence. Also provided is a method of producing protective immunity in an animal or human host in need of such treatment, comprising the step of administering to said animal or human host an effective dose of recombinant mycobacteria carrying the vector of the present invention.


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