Hanwen Mao

Title: The Innovative Contributions of Hanwen Mao

Introduction

Hanwen Mao is a notable inventor based in Annandale, Virginia. He has made significant contributions to the field of genetics and virology, particularly in the development of methods to combat viral infections such as HIV. His innovative approach has the potential to revolutionize therapeutic interventions.

Latest Patents

Hanwen Mao holds a patent for "Methods of inhibiting HIV infectivity." This patent describes a method for identifying host genes and encoded proteins that serve as potential targets for therapeutic intervention. The technique employs a Gene Search Vector, which can be either lentivirus or MMLV-based, allowing for the interrogation of an entire cell genome without prior knowledge of the genomic sequence. This Random Homozygous Gene Perturbation (RUGP) technique is rapidly verifiable and is instrumental in identifying potential host targets for intervention against influenza, HIV, and other viral infections. Notably, the use of Thermal Asymmetric Interlaced (TAIL)-PCR significantly reduces the period for identifying promising targets from months to weeks or less. Specific targets, including PTCH1, Robo1, and Nedd4, are reviewed in detail within the patent.

Career Highlights

Hanwen Mao is associated with Functional Genetics, Inc., where he continues to advance his research and innovations. His work has garnered attention for its potential impact on public health and the treatment of viral diseases.

Collaborations

Hanwen has collaborated with notable colleagues, including Michael Scott Kinch and Michael Goldblatt, who share his commitment to advancing genetic research and therapeutic strategies.

Conclusion

Hanwen Mao's innovative methods and dedication to research exemplify the critical role of inventors in addressing global health challenges. His contributions to the field of virology are paving the way for new therapeutic interventions.