Company Filing History:
Years Active: 1992-1995
Title: The Innovations of Hans Moellering
Introduction
Hans Moellering is a notable inventor based in Tutzing, Germany. He has made significant contributions to the field of biochemistry, particularly through his innovative patents. With a total of 3 patents, Moellering has focused on developing enzymes that have practical applications in various biochemical processes.
Latest Patents
One of his latest patents is titled "Process for the production and use of a stable 6-phosphogluconolactonase." This invention concerns a new 6-phosphogluconolactonase that exhibits an enzyme activity of at least 90% with respect to the initial activity after about 20 hours at pH 7.0 and 20°C. The process described for the production of the enzyme from Leuconostoc highlights its suitability for determining ATP or reaction partners that can be converted into 6-phosphogluconolactone.
Another significant patent is "Pyruvate oxidase mutants, DNA expressing pyruvate oxidase and methods of." This invention provides a pyruvate oxidase that decarboxylates pyruvate to form hydrogen peroxide and is active without the addition of FAD, thiamine pyrophosphate, and divalent metal ions. The amino acid sequence of the enzyme is modified by changing at least one proline in position 178 and alanine in position 458 to a different amino acid. The patent also includes a process for the preparation of this pyruvate oxidase and methods of its use.
Career Highlights
Hans Moellering is currently associated with Boehringer Mannheim GmbH, where he continues to contribute to advancements in enzyme technology. His work has been instrumental in developing innovative solutions that enhance biochemical processes.
Collaborations
Throughout his career, Moellering has collaborated with notable colleagues such as Gunther Schumacher and Georg-Burkhard Kresse. These collaborations have further enriched his research and development efforts.
Conclusion
Hans Moellering's contributions to the field of biochemistry through his patents demonstrate his innovative spirit and dedication to advancing enzyme technology. His work continues to have a significant impact on various applications in the industry.