Hanjie Shen

Title: Hanjie Shen: Innovator in Nanopore Sequencing Technology

Introduction

Hanjie Shen is a prominent inventor based in Guangdong, China. He has made significant contributions to the field of biotechnology, particularly in nanopore sequencing methods. With a total of two patents to his name, Shen's work is paving the way for advancements in genetic sequencing technologies.

Latest Patents

Shen's latest patents include a nanopore sequencing method that utilizes rolling circle amplification. This method involves using a single-strand or double-strand ring of nucleic acid as a template to produce an amplified single strand. Under the influence of an electric field, the amplified single strand is introduced into nanopores of the sequencing device, generating an electrical signal for each base. By analyzing the differences in electrical signals caused by various bases, the base sequence of the template nucleic acid can be accurately measured. Another notable patent is for a hooked probe, which includes a method for ligating nucleic acid and constructing a sequencing library. The hooked probe features a target-specific area that pairs complementarily with a portion of the nucleic acid fragment, facilitating the ligation process.

Career Highlights

Throughout his career, Hanjie Shen has worked with notable companies in the biotechnology sector, including MGI Tech Co., Ltd. and BGI Shenzhen. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking research in genetic sequencing.

Collaborations

Shen has collaborated with esteemed colleagues such as Yuan Jiang and Yang Xi. These partnerships have further enhanced his research and development efforts in the field of nanopore sequencing.

Conclusion

Hanjie Shen's innovative work in nanopore sequencing technology is making a significant impact in the field of biotechnology. His patents reflect a commitment to advancing genetic research and improving sequencing methods.