This inventor holds 7 USPTO granted patents, plus 1 CIPO patent. Top assignees: The Wistar Institute, The Children's Hospital of Philadelphia, Pfizer Corporation. Active years: 1987-2001.
Location History:
- Wynnwood, PA (US) (1987)
- Philadelphia, PA (US) (1997 - 2001)
Company Filing History:



Years Active: 1987-2001
Title: H Fred Clark: Innovator in Vaccine Development
Introduction
H Fred Clark is a prominent inventor based in Philadelphia, PA (US), known for his significant contributions to vaccine development. With a total of 7 patents, he has made remarkable strides in the field of immunology, particularly in the creation of vaccines for various viral infections.
Latest Patents
Among his latest patents is the invention of a rotavirus reassortant vaccine. This innovative vaccine provides novel rotavirus reassortants, vaccines employing these reassortants, and methods for their preparation and administration. One of the reassortants contains the gene encoding the v.p.7 neutralization antigen of a human rotavirus, while another contains the gene encoding the v.p.4 neutralization antigen. The remaining genes are derived solely from the bovine rotavirus WC3 strain or from both human and bovine strains. Additionally, he has developed an aqueous solvent-based encapsulation of a bovine herpes virus type-1 subunit vaccine. This invention discloses a microencapsulated subunit component from bovine herpes virus-1 (BHV-1) and includes vaccines, kits, and methods for vaccinating members of the bovine species.
Career Highlights
H Fred Clark has worked with esteemed organizations such as The Wistar Institute and The Children's Hospital of Philadelphia. His work at these institutions has been pivotal in advancing vaccine research and development.
Collaborations
Throughout his career, Clark has collaborated with notable figures in the field, including Stanley A Plotkin and Paul A Offit. These collaborations have further enriched his contributions to vaccine innovation.
Conclusion
H Fred Clark's work in vaccine development has had a profound impact on public health, particularly in combating viral infections. His innovative patents and collaborations highlight his dedication to advancing medical science and improving health outcomes.