Guoqiang Lin

Title: Guoqiang Lin: Innovator in Chiral Sulfoxide Preparation

Introduction

Guoqiang Lin is a notable inventor based in Nanjing, China. He has made significant contributions to the field of biochemistry, particularly in the preparation of chiral sulfoxides. His innovative work has implications for the pharmaceutical industry, especially in the development of prazole drugs.

Latest Patents

Guoqiang Lin holds a patent for "Bradyrhizobium monooxygenase and use thereof for preparation of chiral sulfoxide." This invention includes a monooxygenase, a gene encoding the monooxygenase, a recombinant expression vector, and a recombinant transformant. The patent also describes methods for preparing the monooxygenase and optically pure chiral sulfoxides. Notably, the method allows for the asymmetric oxidation of thioether, which is a precursor for prazole drugs. Compared to other methods, the monooxygenase catalyst offers high optical purity, avoids byproduct sulfone generation, and features mild reaction conditions, simple operations, and easy amplification.

Career Highlights

Throughout his career, Guoqiang Lin has worked with prominent organizations, including Jiangsu Aosaikang Pharmaceutical Co., Ltd. and East China University of Science and Technology. His experience in these institutions has contributed to his expertise in the field of biochemistry and patent development.

Collaborations

Guoqiang Lin has collaborated with notable colleagues such as Huilei Yu and Yan Mei Zhang. These partnerships have likely enhanced his research and development efforts in the field.

Conclusion

Guoqiang Lin's innovative work in the preparation of chiral sulfoxides demonstrates his significant impact on the pharmaceutical industry. His contributions continue to advance the field of biochemistry and improve drug development processes.